$180.00

FoxO4-DRI – High-Purity Lyophilized Powder FoxO4-DRI is a cell-permeable, synthetic D-retro-inverso peptide engineered as a targeted senolytic agent. Extensively studied in biogerontology and cellular longevity research, it is designed to selectively disrupt the interaction between the FoxO4 transcription factor and the p53 tumor suppressor protein, thereby inducing targeted apoptosis in damaged, senescent cells while preserving healthy surrounding tissue. Click to view CoA Information

Primary Category: Cellular Aging Research
Primary Research Areas: Targeted senolysis, p53/FoxO4 pathway disruption, tissue microenvironment clearance, and cellular longevity models.
Purity: Greater than 99% verified by HPLC.
Format: Lyophilized powder for precise laboratory reconstitution.

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Disclaimer: This product is for research purposes only. It is not intended for direct human consumption.

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Overview

FoxO4-DRI (D-Retro-Inverso) represents a major advancement in senolytic peptide design. Senescent cells—often referred to as “zombie cells”—accumulate with age, resisting normal cell death pathways while secreting damaging pro-inflammatory factors (SASP) that degrade surrounding tissue architecture. By specifically targeting the molecular machinery that allows senescent cells to survive, FoxO4-DRI serves as a critical research tool for investigating tissue rejuvenation, systemic inflammation reduction, and the fundamental mechanics of cellular aging.

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Disclaimer: This product is for research purposes only. It is not intended for direct human consumption.