{"id":647,"date":"2026-10-05T02:55:18","date_gmt":"2026-10-05T02:55:18","guid":{"rendered":"https:\/\/vmpeptides.com\/?post_type=product&p=647"},"modified":"2026-10-10T00:20:07","modified_gmt":"2026-10-10T00:20:07","slug":"glp-2","status":"publish","type":"product","link":"https:\/\/vmpeptides.com\/es\/producto\/glp-2\/","title":{"rendered":"GLP-2 (30mg)"},"content":{"rendered":"

GLP 2 \u2013 Polvo liofilizado de alta pureza<\/b><\/p>\n

GLP 2 es un p\u00e9ptido sint\u00e9tico novedoso, dise\u00f1ado como agonista dual de los receptores del polip\u00e9ptido insulinotr\u00f3pico dependiente de glucosa (GIP) y del p\u00e9ptido similar al glucag\u00f3n tipo 1 (GLP-1).<\/span> Reconocido como un an\u00e1logo “twincretina” de primer nivel, se utiliza ampliamente en la investigaci\u00f3n metab\u00f3lica para evaluar los efectos sin\u00e9rgicos de la activaci\u00f3n de v\u00edas de doble hormona sobre el control gluc\u00e9mico, la se\u00f1alizaci\u00f3n celular pancre\u00e1tica y la regulaci\u00f3n del tejido adiposo profundo.<\/p>\n

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Aviso legal:<\/b> Este producto es exclusivamente para fines de investigaci\u00f3n. No est\u00e1 destinado al consumo humano directo.<\/p>\n<\/blockquote>","protected":false},"excerpt":{"rendered":"

Efectos y mecanismos clave en investigaci\u00f3n<\/h3>\n
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    Activaci\u00f3n sin\u00e9rgica de doble incretina:<\/span><\/b> A diferencia de los agonistas de un solo receptor, GLP-2 se une simult\u00e1neamente a los receptores GIP y GLP-1 y los activa.<\/span> Los modelos in vitro e in vivo muestran que este agonismo doble produce un efecto sin\u00e9rgico profundo sobre la actividad de las c\u00e9lulas beta pancre\u00e1ticas, aumentando la expresi\u00f3n de insulina y regulando al mismo tiempo la secreci\u00f3n de glucag\u00f3n.<\/span><\/p>\n<\/li>\n

  • \n

    Homeostasis glucorreguladora avanzada:<\/b> En modelos de investigaci\u00f3n que eval\u00faan la resistencia a la insulina, la exposici\u00f3n a GLP-2 estabiliza significativamente los perfiles de glucosa en sangre durante las pruebas de tolerancia. Ayuda a los investigadores a estudiar los mecanismos fisiol\u00f3gicos que reducen la producci\u00f3n hep\u00e1tica de glucosa y aumentan la sensibilidad a la insulina de los tejidos perif\u00e9ricos.<\/p>\n<\/li>\n

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    Se\u00f1alizaci\u00f3n central del apetito y modulaci\u00f3n de la saciedad:<\/b> Los estudios centrados en las v\u00edas neurometab\u00f3licas indican que GLP-2 interact\u00faa con \u00e9xito con los receptores del sistema nervioso central responsables de la regulaci\u00f3n del apetito. Los investigadores lo utilizan para observar retrasos pronunciados en la velocidad de vaciamiento g\u00e1strico y el aumento de marcadores estructurales de saciedad.<\/p>\n<\/li>\n

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    Grasa ect\u00f3pica y degradaci\u00f3n del tejido adiposo:<\/b> M\u00e1s all\u00e1 de la homeostasis sist\u00e9mica del peso, GLP-2 se eval\u00faa activamente por su impacto en los perfiles lip\u00eddicos. La investigaci\u00f3n analiza su capacidad para movilizar los triglic\u00e9ridos almacenados y reducir la acumulaci\u00f3n de grasa ect\u00f3pica, en particular en las zonas de tejido hep\u00e1tico y visceral.<\/p>\n<\/li>\n<\/ul>\n

    Aviso legal:<\/b> Este producto es exclusivamente para fines de investigaci\u00f3n. No est\u00e1 destinado al consumo humano directo.<\/p>","protected":false},"featured_media":652,"comment_status":"open","ping_status":"closed","template":"","meta":{"nf_dc_page":"","_monsterinsights_skip_tracking":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[26],"product_tag":[],"class_list":["post-647","product","type-product","status-publish","has-post-thumbnail","product_cat-metabolic-pathway-research","desktop-align-left","tablet-align-left","mobile-align-left","first","instock","taxable","shipping-taxable","purchasable","product-type-simple"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/vmpeptides.com\/es\/wp-json\/wp\/v2\/product\/647","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vmpeptides.com\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vmpeptides.com\/es\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/vmpeptides.com\/es\/wp-json\/wp\/v2\/comments?post=647"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vmpeptides.com\/es\/wp-json\/wp\/v2\/media\/652"}],"wp:attachment":[{"href":"https:\/\/vmpeptides.com\/es\/wp-json\/wp\/v2\/media?parent=647"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/vmpeptides.com\/es\/wp-json\/wp\/v2\/product_brand?post=647"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vmpeptides.com\/es\/wp-json\/wp\/v2\/product_cat?post=647"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vmpeptides.com\/es\/wp-json\/wp\/v2\/product_tag?post=647"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}